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The genetic polymorphism ALDH2*2 affects ≈50% of the Asian population and results in a diminution in ALDH2 activity (Goedde and Agarwal, 1987

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Another randomized controlled trial of patients undergoing surgery for esophageal cancer showed that EPA-enriched enteral nutrition, given preoperatively and postoperatively, significantly protected against lean body mass (with significantly less postoperative lean body mass loss in the EPA group), resulting in an overall weight loss of only about 1.2 kilograms (compared to 1.9 kilograms in the control group) (74)